1. Name of the genetic disease
It is the most common sickle cell disease it is a serious disorder in which the body makes sickle-shaped red blood cells.
2. Symptoms of disease
Some people have mild symptoms. Others have very severe symptoms and are sometimes hospitalized for treatment.
shortness of breath, dizziness, headache, and cold in the hands and feet.
3. When is the disease usually detected... at birth or later in life?
it is present at birth but most common after 4 months of age
4. Frequency of carriers of this disease in the population
African Americans people are the most common carriers of this disease
5. Frequency of disease in the population
1 out of every 500 African American births.
6. Mode of inheritance. Is disease dominant, recessive, sex-linked or due to non-disjunction?
People who have the disease inherit two genes for sickle hemoglobin—one from each parent.
7. Is disease autosomal (on the first 22 pairs of chromosomes), or is it on the X-linked or sex chromosomes?
It is x-linked recessive genetic disorder
8. What chromosome number has been determined to carry this gene?
it is on the x chromosome
9. What treatment, if any, is used for this disease? How does the treatment affect the disease?
Blood and marrow stem cell transplants. It replaces a person's abnormal stem cells with healthy ones.
10. What is the prognosis or outlook for your baby's recovery?
If treated with antibiotics, it greatly improves a child's outcome.
11. What future techniques might be used to correct or eliminate your baby's disease?
Genetic counseling
12. Discuss in detail what difficulties, if any, a parent would encounter in raising a child with this disease.
Body-image problems caused by delayed sexual maturity. Coping with pain and fear of addiction from using strong pain medicines. Living with uncertainty about pain and damage to a person's body.
13. Include diagrams of your child or factors related to your disease.
Example of an Inheritance Pattern for Sickle Cell Trait
The image shows how sickle hemoglobin genes are inherited. A personinherits two hemoglobin genes—one from each parent. A normal gene willmake normal hemoglobin (A). A sickle hemoglobin gene will make abnormalhemoglobin (S).
1. Name of the genetic disease
It is the most common sickle cell disease it is a serious disorder in which the body makes sickle-shaped red blood cells.
2. Symptoms of disease
Some people have mild symptoms. Others have very severe symptoms and are sometimes hospitalized for treatment.
shortness of breath, dizziness, headache, and cold in the hands and feet.
3. When is the disease usually detected... at birth or later in life?
it is present at birth but most common after 4 months of age
4. Frequency of carriers of this disease in the population
African Americans people are the most common carriers of this disease
5. Frequency of disease in the population
1 out of every 500 African American births.
6. Mode of inheritance. Is disease dominant, recessive, sex-linked or due to non-disjunction?
People who have the disease inherit two genes for sickle hemoglobin—one from each parent.
7. Is disease autosomal (on the first 22 pairs of chromosomes), or is it on the X-linked or sex chromosomes?
It is x-linked recessive genetic disorder
8. What chromosome number has been determined to carry this gene?
it is on the x chromosome
9. What treatment, if any, is used for this disease? How does the treatment affect the disease?
Blood and marrow stem cell transplants. It replaces a person's abnormal stem cells with healthy ones.
10. What is the prognosis or outlook for your baby's recovery?
If treated with antibiotics, it greatly improves a child's outcome.
11. What future techniques might be used to correct or eliminate your baby's disease?
Genetic counseling
12. Discuss in detail what difficulties, if any, a parent would encounter in raising a child with this disease.
Body-image problems caused by delayed sexual maturity. Coping with pain and fear of addiction from using strong pain medicines. Living with uncertainty about pain and damage to a person's body.
13. Include diagrams of your child or factors related to your disease.
Example of an Inheritance Pattern for Sickle Cell Trait